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WASHINGTON Wholesale China Jerseys , July 11 (Xinhua) -- Bacteria carrying the MCR-1 "superbug" gene, which makes the last-resort antibiotic colistin useless against them, have been found in a second U.S. patient, researchers said Monday.


The gene was detected in an isolate of Escherichia coli that was originally recovered in 2015 from a patient in New York, according to the research published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.


Previously Wholesale Jerseys Cheap , Escherichia coli bacteria carrying the MCR-1 gene was identified in a urine sample from a Pennsylvania woman with no recent travel outside of the U.S. this May.


The mcr-1 gene makes bacteria resistant to the antibiotic colistin, which is used as a last-resort drug to treat patients with multi-drug-resistant infections, including carbapenem-resistant Enterobacteriaceae (CRE).


U.S. health experts said the discoveries would be concerning because the mcr-1 gene exists on a plasmid, a small piece of DNA that is capable of jumping between different bacterial species, spreading any resistance genes it carries.


In the current study, the researchers Wholesale Jerseys Free Shipping , who coordinated the worldwide SENTRY Antimicrobial Surveillance Program, first tested 13,526 Escherichia coli and 7,480 Klebsiella pneumoniae strains that had been collected from hospitals in the Asia-Pacific region, Latin America, Europe Wholesale Jerseys From China , and North America in 2015.


They found that 390, or 1.9 percent, were resistant to colistin, and that 19 of these isolates tested positive for mcr-1.


The 19 isolates originated in ten countries representing all of the above regions. It involved a New York patient infected with Escherichia coli whose name was not disclosed.


The isolates that tested positive for mcr-1 were susceptible to several commonly used antimicrobial agents, including carbapenems, and recently approved anti-microbial agents that can be used against gram negative bacteria Wholesale Jerseys China , said corresponding author Mariana Castanheira, Director for Molecular and Microbiology at Iowa-based JMI Laboratories.


That means these and similar isolates are unlikely to cause hard to treat infections at this time, Castanheira noted.


The presence of the mcr-1 gene, however, and its ability to share its colistin resistance with other bacteria such as CRE raised the risk that pan-resistant bacteria could develop, the U.S. Centers for Disease Control and Prevention said earlier.


The mcr-1 gene was first isolated from food animals and humans in China in late 2015. Following that Wholesale Jerseys , scientists across the globe began searching for other bacteria containing the mcr-1 gene, and the bacteria have since been discovered in Europe and Canada.

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